High-Density Lipoprotein and Plaque Regression
نویسندگان
چکیده
منابع مشابه
High - Density Lipoprotein and Atherosclerosis Regression
High-density lipoproteins (HDL) are typically defined as lipoprotein particles with buoyant densities from 1.063 to 1.21 g/mL and having apolipoprotein AI (apoAI) as the major apolipoprotein species. It has become increasingly appreciated that the HDL population consists of a collection of particles with diverse sizes, structures, and composition and functional properties that are thought to in...
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It has been proven beyond all reasonable doubt that lowering the level of low density lipoprotein cholesterol (LDL-C) reduces cardiovascular morbidity and mortality (1–7). This benefit has been demonstrated in both a primary and secondary prevention setting and has been observed in hard end point and in regression studies. Benefits are apparent both in subjects with hypercholesterolemia and in ...
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Primary and secondary prevention of coronary heart disease (CHD) has focused on lowering the LDL fraction of blood lipids not only because of the strong epidemiological evidence linking LDL to CHD, but also because pharmacological interventions have made it a highly modifiable risk factor. In contrast, although there is compelling epidemiological evidence that a low plasma level of HDL is also ...
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CONTEXT Statins reduce low-density lipoprotein cholesterol (LDL-C) levels and slow progression of coronary atherosclerosis. However, no data exist describing the relationship between statin-induced changes in high-density lipoprotein cholesterol (HDL-C) and disease progression. OBJECTIVE To investigate the relationship between changes in LDL-C and HDL-C levels and atheroma burden. DESIGN, S...
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ژورنال
عنوان ژورنال: Circulation
سال: 1999
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.100.17.1762